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December 11, 2006

Leptospirosis

Filed under: General — DrMark @ 11:58 am

What is Leptospirosis?

Leptospirosis is a bacterial disease that affects humans and animals. It is caused by bacteria of the genus Leptospira. In humans and pets it causes a wide range of symptoms, and some infected persons may have no symptoms at all. Symptoms of leptospirosis include high fever, severe headache, chills, muscle aches, and vomiting, and may include jaundice (yellow skin and eyes), red eyes, abdominal pain, diarrhea, or a rash. If the disease is not treated, the patient could develop kidney damage, meningitis (inflammation of the membrane around the brain and spinal cord), liver failure, and respiratory distress. In rare cases death occurs. Many of these symptoms can be mistaken for other diseases. Leptospirosis is confirmed by laboratory testing of a blood or urine sample.

How do people get leptospirosis?

Outbreaks of leptospirosis are usually caused by exposure to water contaminated with the urine of infected animals. Many different kinds of animals carry the bacterium; they may become sick but sometimes have no symptoms. Leptospira organisms have been found in cattle, pigs, horses, dogs, rodents, and wild animals. Humans become infected through contact with water, food, or soil containing urine from these infected animals. This may happen by swallowing contaminated food or water or through skin contact, especially with mucosal surfaces, such as the eyes or nose, or with broken skin. The disease is not known to be spread from person to person.

How long is it between the time of exposure and when people become sick?

The time between a person’s exposure to a contaminated source and becoming sick is 2 days to 4 weeks. Illness usually begins abruptly with fever and other symptoms. Leptospirosis may occur in two phases; after the first phase, with fever, chills, headache, muscle aches, vomiting, or diarrhea, the patient may recover for a time but become ill again. If a second phase occurs, it is more severe; the person may have kidney or liver failure or meningitis. This phase is also called Weil’s disease. The illness lasts from a few days to 3 weeks or longer. Without treatment, recovery may take several months.

Where is leptospirosis found?

Leptospirosis occurs worldwide but is most common in temperate or tropical climates. It is an occupational hazard for many people who work outdoors or with animals, for example, farmers, sewer workers, veterinarians, fish workers, dairy farmers, or military personnel. It is a recreational hazard for campers or those who participate in outdoor sports in contaminated areas and has been associated with swimming, wading, and whitewater rafting in contaminated lakes and rivers. The incidence is also increasing among urban children and pets.

How is leptospirosis treated?

Leptospirosis is treated with antibiotics, such as doxycycline or penicillin, which should be given early in the course of the disease. Other drugs may be more effective in treating the carrier state. Intravenous antibiotics may be required for patients with more severe symptoms. Persons with symptoms suggestive of leptospirosis should contact a health care provider.

Can leptospirosis be prevented?

The risk of acquiring leptospirosis can be greatly reduced by not swimming or wading in water that might be contaminated with animal urine. Protective clothing or footwear should be worn by those exposed to contaminated water or soil because of their job or recreational activities.

How can my pet be protected from Leptospirosis?

This disease was previously thought of as only a “farm dog” disease as it was most prevalent in rural pets that had close contact with livestock and feed storage areas that harbored rodents. Now more cases are seen in suburban pets than in rural pets! Homes are built in areas that raccoons and other wildlife exist. These animals frequently try to find a free meal left out for an outdoor dog or cat and wind up contaminating with Leptospira bacteria the environment by urinating in areas that pets will have contact. Dogs that are at risk for contact with such animals should be vaccinated with a “4-way” Leptospirosis vaccine. Using the older “2-way” lepto vaccine does not prevent the more common species of Leptospirosis disease currently seen in veterinary practise. There is currently no vaccine for cats. It is extremely uncommon for cats to develop disease, though it is unkown the percent of subclinically infected cats that exist. However, cats can be experimentally infected with Leptospirosis bacteria and have been shown to be chronic carriers of such infections. Keep pets away from wildlife such as raccoons, armadillos, opossums, voles, wolfes, foxes, deer, and skunks, as well as from rodents.

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